Abstract CarH is a coenzyme B12-dependent photoreceptor involved in regulating carotenoid biosynthesis.How light-triggered cleavage of the B12 Co-C bond culminates in CarH tetramer dissociation to initiate transcription remains unclear.Here, a series of crystal structures of the CarH B12-binding domain after illumination suggest formation of unfore
Abstract This paper provides a simple hybrid design and numerical analysis of the graphene-coated fiber-optic surface plasmon resonance (SPR) biosensor for breast cancer gene-1 early onset (BRCA1) and breast cancer gene-2 early onset (BRCA2) genetic breast cancer detection.Two specific mutations named 916delTT and 6174delT in the BRCA1 and BRCA2 ar
In this work we attempt to find out the extent to which realistic prebiotic compartments, such as Printed Color Hat Misc fatty acid vesicles, would constrain the chemical network dynamics that could have sustained a minimal form of metabolism.We combine experimental and simulation results to establish the conditions under which a reaction network w